Friday, 18 December 2020

COVID-19 Time For An Update On My Treatment For Colds 04 (Revised 2021-03-05 and 31)

Nose blocked, heat added 04
Hand warmer pad 02
    
Band-aid blocker 03
Heating pad heat 01



    

It is time for an update on my treatment for colds. Since April when I posted my first blog on colds I have been searching for clinical evidence that validates my assumptions. I found the limit for the rhinovirus and its 200 or variations but there has not been an equivalent study for the coronaviruses. I found one paper that shows the S spike glycoprotein which helps to connect the virus to the host cell doesn’t work in situ above 37.50C(99.5F)which means the virus Cov2 can’t connect. It is not clear what happens to the virus but it seems to be killed at above this temperature and humidity making it more sensitive just above the human average normal temperature.

While I assumed from one paper that most of the replications occurred in the nasopharynx at the back of the nose, of the upper respiratory tract, it can also reproduce before that at the top of the nose in the smell sensory area. It can also happen below these areas and just above the tongue. Hence the loss of smell and coughing.

Another point I found was that the average temperature of humans is dropping below 370C. My temperature is around 36.3 and 36.60C(97.3-97.9F). This temperature difference is enough to make older folks vulnerable to the third stage after the virus stage stops shedding. The lungs and central nervous systems become compromised.

Heat when applied to colds by breathing saturated air at 430C(109.4F) for 20 minutes per 2 to 3 intervals has been tested on rhinovirus over 20 years ago with an 80% success rate.  By applying heat by direct conduction to the bone and cartilage to the infected is more efficient and doesn't require sophisticated equipment. The process is to extend the natural effect of a fever, to an area that is normally cooled by incoming air which compromises the fever effectiveness.  I have found that the symptoms drop off overnight. 

What I am getting to is that it is best to combine my last 3 posts to get the best results. That is to add extra heat, blocking the nose closed, where to apply the heat and how to make a hand warming pouch . This will make my treatment most effective particularly for older people. There are still some caveats below with some redundancy from the last post. I believe this treatment is viable.  

In simplified terms: 

1.  get a heat source of your choice as suggested, 

2.  plug your nose, breathe through your mouth.

3. hold the heat source of your choice, on your face for the designated time and location, 

4. Times up, remove nose plug tape, 

5. Clear your nose as needed.  

The caveats: There are some rules. 

  • You should have a fever, preferably defined as high. Fever is your friend.
  • You have recently tested positive for COVID-19 Asymptomatic or symptomatic.
  • You have a newly acquired cough, sore throat, runny nose, sore sinuses, loss of sense of smell.
  • This must be applied within the first week of any of the above.
  • Should not be applied under very high fever conditions (cytokine storm).
  • Don’t take any aspirin, acetaminophen (paracetamol), or ibuprofen as they lower the fever.
  • Repeat the process the next day if necessary. ( If stored properly, hand-warmers work for 6 to 10 hours and can be stored if sealed in a plastic bag.)
  • A maximum direct heat application of 41-420C is sufficient.
  • Keep warm, wear a hat, sweater, and scarf.
  • Be smart! Wear a mask until everyone is vaccinated.

Me, fooling around, 2 hats, 3 neck warmers
Checking Temperature Effects
It warms the incoming air 
        Some References

1.                  1.  - Why is temperature sensitivity important for the success of common respiratory viruses?                       Eccles R.,      Rev Med Virol. 2020;e02153. https://doi.org/10. 1002/rmv.2153

 

2.            2. -Body temperature and host species preferences of SARS-CoV-2.

                 Uzoigwe, Chika Edward     https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(20)30424-9/pdf

      

     3.   -The Effects of Temperature and Relative Humidity on the Viability of the SARS                        coronavirus,    K. H. Chan, et al,  https://www.hindawi.com/journals/av/2011/734690/

     4.   -Role of fever and ambient temperature in COVID-19

               Muhammad Hamdan Gul,a Zin Mar Htun,b and Asad Inayat


 

     5.   -Animal and translational models of SARS-CoV-2 infection and COVID-19                           

        M. D.     Johansen1, et al,

        Mucosal Immunology (2020) 13:877–891; https://doi.org/10.1038/s41385-020-00340-z 

 

    6.  -Fever and the thermal regulation of immunity: the immune system feels the heat                                             Sharon S. EvansElizabeth A. Repasky, and Daniel T. Fisher

                    HHS Author Manuscripts   PMC4786079

  7.  Protective Facemask Impact on Human Thermoregulation: An Overview
         
         Raymond J. Roberge*, Jung-Hyun Kim and Aitor Coca
        https://doi.org/10.1093/annhyg/mer069

1 comment:

  1. This is a test by me. Alan you have created an incredible solution to an insoluble problem. Thank you.
    Hold on, do I hear someone disputing this outrageous claim. There should be at least a thumbs up or down.

    ReplyDelete